Saturday, May 31, 2014

Lipomas (pathophysiology via med ref)

Lipomas are common benign mesenchymal tumors. They may develop in virtually all organs throughout the body. In the gastrointestinal tract, lipomas present as submucosal fatty tumors. The most common locations include the esophagus, stomach, and small intestine. Symptoms occur from luminal obstruction or bleeding. Duodenal lipomas are mostly small but may become pedunculated with obstruction of the lumen. They may cause pain, obstructive jaundice, or intussusception in younger patients.[5] Mucosal erosion over the lipoma may lead to severe bleeding, as demonstrated in the image below. Small intestinal lipomas occur mainly in elderly patients. They tend to be pedunculated submucosal lesions. They are more common in the ileum than in the duodenum or jejunum. As with duodenal lipomas, severe hemorrhage or intussusception may occur. Colonic lipomas are usually discovered on endoscopy. Gentle palpation with a biopsy forceps reveals the soft nature of the submucosal mass. A biopsy specimen of the mucosa may reveal underlying fat, the so-called naked fat sign. As with lipomas in other locations, colonic lipomas may cause pain with obstruction or intussusception.
As noted above, a fatty protrusion of preperitoneal fat termed a "lipoma of the spermatic cord" is a common finding on groin exploration for hernia repair. Numerous case reports document the presence of lipomas in other, rare locations, with these tumors having been found virtually everywhere in the body.[6, 7, 8, 9, 10] Lipomatous involvement of endocrine organs, including the thyroid, adrenal glands, pancreas, and parathyroid glands, has been described. Maxillofacial lipomas, including intralingual, parotid, orbitonasal, maxillary sinusoidal, and parapharyngeal space masses, have also been documented. In rare instances, intraosseous and intra-articular involvement occurs. Involvement of the structural components of the mediastinum, including the airways and pleura, has also been reported. Gynecolic lipomas may occur in the uterus, ovaries, and broad ligament. Critical organ involvement of the heart (causing ventricular tachycardia), superior vena cava, brain, and spinal cord may pose a significant clinical challenge.[11, 12] Mixed histologies, such as angiolipomas and fibrolipomas, are often encountered and are usually benign. Differentiation from liposarcoma may be difficult. Other fatty tumors include lipoblastomas, hibernomas, atypical lipomatous tumors, and liposarcomas. Lipoblastomas occur almost exclusively in infants and children. They have a benign clinical course and a low recurrence rate after surgical excision. Hibernomas, also rare, derive their name from the morphologic resemblance to the brown fat of hibernating animals. They presumably arise from fat that may occur in the back, hips, or neck in adults and infants. Atypical lipomatous tumors are generally considered to be low-grade sarcomas, with a strong propensity to recurrence but little metastatic potential. Liposarcomas are true mesenchymal malignancies.

Thursday, May 29, 2014

Filling in the pieces... Adipose Tissue Disorder

When I was young, constantly plagued by allergies. Mostly sinus related like common rhinitis and skin reactions to grasses. I was very susceptible to colds. And every cold I ever had went to my chest and turned into bronchitis. My mother recalls feeling sympathetic, I recall her screaming to blow my nose.

My period didn't begin until after my 16th birthday but once it did it was a nightmare.  Periods were  irregular, blood loss was always severe, heavy tissues and clots required a number of D&Cs. I eventually began birth control that stopped my periods completely. Discontinuing proved to be more of a nightmare & suffered 2 miscarriages thereafter.

Concerning my 3 children: the first delivery was to be natural but as my daughter was over 8lbs we each experienced some difficulty as she was in the birth canal & had an emergency c-section(89). My second child & I suffered a complicated pregnancy & it was questionable but would try natural delivery which didn't work either and it was only discovered after my insistence upon delivery that he actually harbored a grapefruit size tumor in his liver(90). My youngest son and I experienced placenta previa, amino, and a period of hospitalization prior to his c-section delivery(97).

I was ejected from a vehicle on the way to high school graduation causing spinal injury . And upon chiropractic rehabilitation visits discovered schuerrman's spine, mild scoliosis, and early arthritis diagnoses.

Debilitating migraine headaches began in my early 20's. Including all the classic signs plus vomitting & sustained fatigue afterwards.

During my 30s the migraines escalated more frequent, more pronounced, and for longer durations causing complete lockdown and imitrex injections.

I had 2 separate "attacks" / "episodes" sandwiching a period of confusion, brain fog, inability to function mentally at the prior level, becoming overwhelmed by outside stimuli and severe eye sensitivity to light & skin reactions. Both attacks were medically observed. The first  attack was described as migraine related ezcemic (sp?) occurrence.. When one side of my face had swollen quite large as though I was having an allergic reaction of some sort (but was not). The 2nd was called a palsy, when one side of my face drooped and lost elastisty.  Both the swelling and the dropped face issues resolved.  However, the other symptoms continued for a few weeks although I still have lingering difficulties with brain fog and the like.

Beginning in my late 20s began to have a number of abdominal issues. At least twice visiting the ER for pain intervention. Given GI cocktails with lidocaine.

Discovered new dietary intolerances ; bok Choy & the like.

30s found first lipoma in thigh, told it wasn't anything to be too concerned about. Many more began to be palpable in my arms & trunk.

suspicious mole biopsy clear. Lipoma from upper arm removed biopsy noncancerous.

Dr recommended : Herbs to aid lung health

Below is a list of herbs that can not only boost lung and respiratory health but can also repair it. Herb information is courtesy of John Summerly who is nutritionist, herbologist, and homeopathic practitioner. 1. Licorice Root Licorice is one of the more widely consumed herbs in the world. In Traditional Chinese Medicine it occurs in more formulas than any other single herb because it is thought to harmonize the action of all other herbs. Licorice is very soothing and softens the mucous membranes of the throat and especially the lungs and stomach and at the same time cleanses any inflamed mucous membrane that needs immune system support . It reduces the irritation in the throat and yet has an expectorant action. It is the saponins (detergent-like action) that loosen the phlegm in the respiratory tract so that the body can expel the mucus. Compounds within this root help relieve bronchial spasms and block the free radical cells that produce the inflammation and tightening of the air ways. The compounds also have antibacterial and antiviral effects to them as well which helps fight off viral and bacterial strains in the body that can cause lung infections. Glycrrhizins and flavonoids can even help prevent lung cancer cells from forming which means they can even prevent lung cancer. 2. Coltsfoot Coltsfoot has been traditionally used by Native Americans for thousands of years to strengthen the lungs. It clears out excess mucus from the lungs and bronchial tubes. It soothes the mucus membranes in the lungs, and has been shown in research to assist with asthma, coughs, bronchitis, and other lung ailments. Coltsfoot is available in dried form for tea or as an alcohol extract known as a tincture. 3. Cannabis The toxic breakdown of therapeutic compounds in cannabis from burning the plant are totally avoided with vaporization. Extraction and inhaling cannabinoid essential oils of the unprocessed plant affords significant mitigation of irritation to the oral cavity that comes from smoking. Cannabis is perhaps one of the most effective anti-cancer plants in the world shown in study after study to stimulate cannabinoid receptor activation in specific genes and mediate the anti-invasive effect of cannabinoids. Vaporizing cannabis allows the active ingredients to stimulate the body’s natural immune response and significantly reduces the ability of infections to spread. Vaporizing cannabis (especially with very high amounts of cannabinoids) opens up airways and sinuses, acting as a bronchodilator. It is even a proven method to treat and reverse asthma. 4. Osha Root Osha is a herb native to the Rocky Mountain area and has historically been used by the Native Americans for respiratory support. The roots of the plant contain camphor and other compounds which make it one of the best lung-support herbs in America. One of the main benefits of osha root is that it helps increase circulation to the lungs, which makes it easier to take deep breaths. Also, when seasonal sensitivities flare up your sinuses, osha rootm, which is not an actual antihistamine, does produce a similar effect and may be help calm respiratory irritation. 5. Thyme Thyme is very powerful in the fight against chest congestion. It produces powerful antiseptic essential oils which are classified as naturally antibiotic and anti-fungal. Thyme is well known to zap acne more so than expensive prescription creams, gels and lotions. Thyme tea has the power to chase away and eliminate bacteria and viruses so whether your infection is based on either, it will work. Thyme has been used as a lung remedy consumed since antiquity and is used extensively today to prevent and treat respiratory tract infections and bacterial infection pneumonia. 6. Oregano Although oregano contains the vitamins and nutrients required by the immune system, its primary benefits are owed to its carvacrol and rosmarinic acid content. Both compounds are natural decongestants and histamine reducers that have direct, positive benefits on the respiratory tract and nasal passage airflow. Oil of oregano fights off the dangerous bacteria Staphylococcus aureus, better than the most common antibiotic treatments. Oregano has so many health benefits that a bottle of organic oregano oil should be in everyone’s medicine cabinet. 7. Lobelia Did you know that horses given lobelia are able to breathe more deeply? Its benefits are not limited to equestrians. It has been used as “asthmador” in Appalachian folk medicine. Lobelia, by some accounts, is thought to be one of the most valuable herbal remedies in existence. Extracts of Lobelia inflata contain lobeline, which showed positive effects in the treatment of multidrug-resistant tumor cells. Lobelia contains an alkaloid known as lobeline, which thins mucus, breaks up congestion. Additionally, lobelia stimulates the adrenal glands to release epinephrine, in effect, this relaxes the airways and allows for easier breathing. Also, because lobelia helps to relax smooth muscles, it is included in many cough and cold remedies. Lobelia should be part of everyone’s respiratory support protocol! 8. Elecampane Elecampane has been used by Native Americans for many years to clear out excess mucus that impairs lung function. It is known as a natural antibacterial agent for the lungs, helping to lessen infection particularly for people who are prone to lung infections like bronchitis. Herbal practitioners often recommend one teaspoon of the herb per cup of boiling water, drunk three times daily for two to three weeks. Elecampane is also available in tincture format for ease. 9. Eucalyptus Native to Australia, eucalyptus isn’t just for Koala bears! Aborigines, Germans, and Americans have all used the refreshing aroma of eucalyptus to promote respiratory health and soothe throat irritation. Eucalyptus is a common ingredient in cough lozenges and syrups and its effectiveness is due to a compound called cineole. Cineole has numerous benefits — it’s an expectorant, can ease a cough, fights congestion, and soothes irritated sinus passages. As an added bonus, because eucalyptus contains antioxidants, it supports the immune system during a cold or other illness. 10. Mullein Both the flowers and the leaves of the mullein plant are used to make an herbal extract that helps strengthen the lungs. Mullein is used by herbal practitioners to clear excess mucus from the lungs, cleanse the bronchial tubes, and reduce inflammation that is present in the respiratory tract. A tea can be made from one teaspoon of the dried herb to one cup of boiled water. Alternatively, you can take a tincture form of this herb. 11. Lungwort Lungwort is a tree-growing lichen that actually resembles lung tissue in appearance. However, this natural remedy doesn’t just look the part. As early as the 1600′s, lungwort has been used to promote lung and respiratory health and clear congestion. Pulmonaria selections come in all kinds so seek a herbologist for direction. Lungwort also contains compounds that are powerfully effective against harmful organisms that affect respiratory health. 12. Chaparral Chaparral, a plant native to the Southwest, has been appreciated by the Native Americans for lung detoxification and respiratory support. Chaparral contains powerful antioxidants that resist irritation and NDGA which is known to fight histamine response. NDGA inhibits aerobic and anaerobic glycolysis (the energy-producing ability) of cancer cells. Chaparral is also a herb that fights harmful organisms. The benefits of chaparral are mostly available in a tincture extraction but chaparral tea may support respiratory problems by encouraging an expectorant action to clear airways of mucus. 13. Sage Sage’s textured leaves give off a heady aroma, which arises from sage’s essential oils. These oils are the source of the many benefits of sage tea for lung problems and common respiratory ailments. Sage tea is a traditional treatment for sore throats and coughs. The rich aromatic properties arising from sage’s volatile oils of thujone, camphor, terpene and salvene can be put to use by inhaling sage tea’s vapors to dispel lung disorders and sinusitis. Alternatively, brew a strong pot of sage tea and place it into a bowl or a vaporizer. 14. Peppermint Peppermint, and peppermint oil, contains menthol — a soothing ingredient known to relax the smooth muscles of the respiratory tract and promote free breathing. Dried peppermint typically contains menthol, menthone, menthyl acetate, menthofuran and cineol. Peppermint oil also contains small amounts of many additional compounds including limonene, pulegone, caryophyllene and pinene. Paired with the antihistamine effect of peppermint, menthol is a fantastic decongestant. Many people use therapeutic chest balms and other inhalants that contain menthol to help break up congestion. Additionally, peppermint is an antioxidant and fights harmful organisms. 15. Plantain Leaf With fruit that is similar in appearance to a banana, plantain leaf has been used for hundreds of years to ease cough and soothe irritated mucous membranes. Many of its active constituents show antibacterial and antimicrobial properties, as well as being anti-inflammatory and antitoxic. Clinical trials have found it favorable against cough, cold, and lung irritation. Plantain leaf has an added bonus in that it may help relieve a dry cough by spawning mucus production in the lungs. Sources: 1. http://www.everygreenherb.com/lungs.html 2. http://www.sciencedaily.com/releases/2010/02/100209183337.htm?utm_source=twitterfeed&utm_medium=twitter 3. https://www.sciencenews.org/article/antibiotics-may-make-fighting-flu-harder 5. http://thegoodnewsnp.com.au/files/45th_

Sunday, May 25, 2014

Its all related.. beginning with Scheurrmans spine to Osteochrondritis / My right side including arm, shoulder, knee, hip, rib cage & liver. NOW ESOPHAGUS!

http://en.m.wikipedia.org/wiki/Osteochondritis

OSTEO-CHONDRITIS DISSECANS This is an unusual condition that develops in the last few years of growth, and is thought to occur because a small segment of the joint surface loses its blood supply long enough, or repeatedly enough, to become separated from the main body of the bone. The joint surface (articular cartilage) remains intact for a few months to several years, but when it splits around the margins of the lesion, the fragment of bone and articular cartilage separates and becomes an osteo-chondral loose body. This may click and cause discomfort and/or swelling. It may also dislodge and get jammed between the bones causing episodes of locking. The treatment is either to replace the fragment back in the crater it came from, and try to get it to heal, or if it is thought that is not going to succeed, or has already failed, then to just remove the loose body. That still leaves the question of the crater. If it is quite small, no further treatment may be necessary. If, on the other hand, the remaining crater is large enough to cause ongoing symptoms, or if it is lie that early arthritis will result, then it is desirable to find another way of trying to heal the defect. The most popular technique these days is to take some of the healthy articular cartilage from the joint, culture it in the lab for about 6 weeks, and then do what is called an Autologous Chondrocyte Impantation (ACI). If, as is usually the case these days, the graft comes on a collagen patch (matrix), then it is called Matrix Autologous Chondrocyte Impantation (MACI).

Bad Tissue! Bad Adipose Tissue !

The Role of Dysfunctional Adipose Tissue Authors Abstract Overweight and obesity are health problems of epidemic proportions, increasing the risk not only of cardiovascular disease and type 2 diabetes mellitus but also of various types of cancer. Obesity is strongly associated with changes in the physiological function of adipose tissue, leading to insulin resistance, chronic inflammation, and altered secretion of adipokines. Several of these factors, such as insulin resistance, increased levels of leptin, plasminogen activator inhibitor-1, and endogenous sex steroids, decreased levels of adiponectin, and chronic inflammation, are involved in carcinogenesis and cancer progression. This article reviews these mechanisms, focusing on adipose tissue dysfunction as a unifying causal factor. Although understanding of the link between obesity and cancer might provide therapeutic targets, preventing overweight and obesity still remains number one priority. (Cancer Epidemiol Biomarkers Prev 2009;18(10):2569–78) Footnotes Grant support: Grant from the Leatare Foundation, Monaco, and the Catharijne Foundation, the Netherlands. Received April 20, 2009. Revision received July 7, 2009. Accepted August 10, 2009. Published OnlineFirst September 15, 2009; doi: 10.1158/1055-9965.EPI-09-0372 Cancer Epidemiol Biomarkers Prev October 2009 18; 2569 » Abstract Full Text Full Text (PDF) All Versions of this Article: 1055-9965.EPI-09-0372v1 18/10/2569 most recent

Try for Tietzes...

(2 excerpts below from UK to assist)

Tietzes syndrome cure (hopefully) Posted over a year ago Have suffered for years like most of you on this forum i wont bore you with the details e.r, codiene, steriod shots etc... What i have found what works for me is calcium orotate, yes it is expensive but it has given me my life back and compared to the amount of months i have to have off work when i get an attack it's worth it really, two years ago i was ready to kill myself as i could no longer live with the pain but this has changed my life i'm not saying i dont get the odd twinges because i do, but then i increase the dose for a few days and the pains die back down. It is not an instant cure you have to give it a few weeks to get into the cartilage, Anyway go try what do you have to lose, would love to know if it works for other people too. 

(dercums complication, breathing factors combined with frontal enclosed posture tendencies, forward rolling shoulders)

Tietze Syndrome

Posted over a year ago

I have a possible treatment for anyone with Tietze Syndrome to try. I had it for about 10 months and was in severe pain. I couldn't even breath deeply or sneeze, or pick things up without extreme pain. I also had a lot of inflammation and upper back pain.

I came to realize that my poor posture was causing the problem after many consultations with doctors, physiotherapists and massage therapists. I have very rounded shoulders.

You can test to see if you have rounded shoulders by standing with your arms loosely at your side. If your thumbs hang in toward your thighs, then you have rounded shoulders. If you thumbs hang forward then your posture is much better.

My rounded shoulders are caused by very tight chest muscles and weak upper back muscles.

The first thing I had to do toward my healing process was stretch my chest muscles so that they were not always pulling my shoulders in, and also strengthen my upper back muscles so that they would automatically pull my shoulders back more naturally.

I also realized that I sleep on my side at night and hug my arms into my chest so I had to train myself to sleep on my back so that gravity could help my chest relax instead of being tensed up at night.

Stretches to help loosen the chest:

Lie on a physio roller lengthwise with the roller going vertically from your head to your lower back.

Start with your arms down by your sides and slowly raise them straight up over your head until they touch the floor behind you (when I first started I couldn't even come close to touching the floor behind my head because my shoulders were so tight, but over time I loosened up and could touch the floor)

Also try lying the same way on the roller and bring the arms up to the sides of your body kind of like you are making a snow angel all the way to the top of the head keeping arms straight.

I could not believe how much these exercises helped me to loosen my chest muscles and over a few weeks of doing these a few times daily, the pain started to go away.

Now whenever I feel a twinge in my chest, I know that I am getting tight in my chest and I need to keep up the stretches. It really helps. Doing upper back strengthening exercises with weights really helps too.

I don't know if this will work for everyone, but give it some time, it is a very simple solution and is definitely worth a try because I know how depressing the pain can be and now I have been pain free for over a year.

I know it probably seems too simple to work, but it worked for me

Saturday, May 24, 2014

ATD Gene Identified

http://www.sciencedaily.com/releases/2014/05/140522123503.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29#.U4ESWxv2Zk8.facebook