Urticaria

http://meandmymastcells.com/urticaria-pigmentosa/

http://www.formulamedical.com/Topics/Symptoms/skin,%20hives.htm

http://www.aocd-grandrounds.org/case_48.shtml

CORRECT DIAGNOSIS:

Urticaria Pigmentosa

DISCUSSION:

Mastocytosis (MC) is a heterogeneous group of disorders characterized by abnormal proliferation and accumulation of mast cells in the skin, bone marrow, gastrointestinal tract, liver, spleen, and lymph nodes. The spectrum of mast cell disease has been classified based on type and extent of involvement as well as age of onset.

Cutaneous forms include solitary mastocytoma, urticaria pigmentosa, diffuse cutaneous mastocytosis, and telangiectasia macularis eruptiva perstans. Urticaria pigmentosa is the most common form of cutaneous MC. Urticaria pigmentosa (UP) usually presents in childhood and can persist into adulthood, however, most spontaneously improve. 

Patients with UP may also experience various systemic symptoms such as pruritus, flushing, dizziness, palpitations, syncope, nausea, diarrhea, abdominal pain, headache, musculoskeletal pain, and neuropsychiatric disturbances.